Kamigawa: Neon Dynasty contains 302 regular cards (117 commons, 88 uncommons, 59 rares, 18 mythic rares, 20 basic lands) and includes randomly inserted premium versions of all cards.

The setting of Neon Dynasty is described as Magic: The Gathering’s first science fiction plane.

Several Japanese artists were engaged to produce card illustrations, among them famous manga artists like Tetsuo Hara.

The central conflict of the set is the conflict between modernity and tradition – a metafictional reference to how R&D struggled to develop a sequel to one of the worst received blocks of Magic, separating it from the previous setting while making it recognizably the same plane.

Half of the set features the newly mechanized world of modern Kamigawa, while the other half depicts the more traditional Kamigawa.